Novel Drugs & Emergent Therapeutics | Ophthalmology
Time to read: 00: 32 minutes
Originally published: 23 September 2024
Source: PR Newswire
Type of article: Novel Drug & Emergent Therapy News
MedED Catalogue Reference: MNDO008
Category: Opthalmology
Crossreference: Gene Therapy
Category tags:on-anterior non-infectious uveitis (NIU). TYK2 and JAK1
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| Product Category | Product Name | Company | Status |
|---|---|---|---|
| Phase 3,Active Not yet recruiting |
September 23, 2024/ Press Release
Patient-level wide-field fluorescein angiography results indicated a mean decrease in retinal vascular leakage by 4.4 points in the 45 mg group compared to a 0.5-point decrease in the 15 mg group, establishing a clinically meaningful improvement in posterior segment inflammation.
Clinical Trials & Supporting Information
| Clinical Study State | Clinical Trial Registration Number | Study Name |
|---|---|---|
| Active, Not yet recruiting | ClinicalTrials.gov NCT06431373 |
A Study of Brepocitinib in Adults With Active, Non-Infectious, Non-Anterior Uveitis (CLARITY) |
|
A Study of Brepocitinib in Adults With Active Non-Infectious Non-Anterior Uveitis (NEPTUNE) |
Access original press release
23 September 2024,| PR Newswire | Priovant Therapeutics Announces Receipt of Fast Track Designation from FDA for Brepocitinib in Non-Anterior Non-Infectious Uveitis (NIU) & Start of Enrollment of Brepocitinib Phase 3 NIU Program
Access additional information
Rusiñol L, Puig L. Tyk2 Targeting in Immune-Mediated Inflammatory Diseases. Int J Mol Sci. 2023 Feb 8;24(4):3391. doi: 10.3390/ijms24043391. PMID: 36834806; PMCID: PMC9959504.
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