Clinical Trial WATCH | Cardiology
Hybrid Ablation Versus Repeated Catheter Ablation in Persistent Atrial Fibrillation: A Randomized Controlled Trial
Source: JACC Clin Electrophysiol
Date Originally Published: 18 Jan 2023
Type of article:Clinical Trial WATCH
MedED Catalogue Reference: MGCW002
Category: Gerontology | Cardiology
Category Cross-reference: Surgery
Keywords: atrial fibrillation; catheter ablation; hybrid ablation; cardiovascular disease, CVD, AF
This summary is intended to provide a snapshot of the original research. It is in no way a substitute for the original research article, nor is it intended to be a complete reflection of the original research.
Originally published in JACC Clin Electrophysiol.,18 January 2023
This randomised control trial compared the effectiveness and safety of Hybrid Ablation (HA) and Catheter Ablation (CA) in treating persistent atrial fibrillation (persAF).
In a 12-month prospective, randomized trial of 41 ablation-naive patients, HA demonstrated higher freedom from atrial tachyarrhythmias off antiarrhythmic drugs (89% vs. 41%).
Both procedures had comparable safety profiles with few complications. HA, combining thoracoscopic epicardial and transvenous endocardial approaches, proved to be an efficacious and safe alternative, suggesting better outcomes than CA for persistent AF treatment.
ClinicalTrials.gov Identifier: NCT02441738
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