- View Cognitive Motor Dissociation in Disorders of Consciousness Currently reading
In Brief | Neurology & Neurosurgery
Cognitive Motor Dissociation in Disorders of Consciousness
Time to read: 01:44
Time to listen: 03:52
Published on MedED: 24 September 2024
Originally Published: 24 August 2024
Sourced: NEJM
Type of article: In Brief
MedED Catalogue Reference: MNIB001
Category: Neurology
Cross Reference: Critical Care, Gerontology
Keywords: brain injury, TBI, consciousness, EEG, fMRI
fMRI and EEG may detect signs of cognitive activity in brain injury patients who appear unresponsive, suggesting that advanced neuroimaging techniques could offer valuable insights into their cognitive function and treatment potential.
Originally published in NEJM, 24 August 2024 This summary does not represent the original research, nor is it intended to replace the original research. Access the full Disclaimer Information
A recent study published in the New England Journal of Medicine found that patients with brain injuries who do not respond to commands may still exhibit cognitive activity detectable through functional magnetic resonance imaging (fMRI) and electroencephalography (EEG).
According to researchers Bodien &Allanson et al., the phenomenon, termed cognitive motor dissociation (CMD),highlights the potential for hidden cognitive abilities in individuals with disorders of consciousness.
The prospective cohort study took place across six international centres and researchers collected clinical, behavioural, and task-based fMRI and EEG data from 353 adults who had disorders of consciousness.
- The median age of patients included in the study was 37.9 years
- Only 35% had data recorded from both fMRI and EEG
- Brain trauma was the etiologic factor in 50% of cases
- The median time from brain injury to CRS-R assessment was 7.9 months, with 25% of the patients having been assessed within 28 days of injury
- 11 had been assessed with fMRI only,
- 13 with EEG only, and
- 36 were assessed with both techniques.
In contrast, a task-based fMRI or EEG response was recorded in 38% of participants (43 of 112), who furthermore had an observable response to a command
Access the original research article
Back to top
Disclaimer
This article is compiled from several resources researched and compiled by the contributor. It is in no way presented as an original work. Every effort has been made to attribute quotes and content correctly. Where possible all information has been independently verified. The Medical Education Network bears no responsibility for any inaccuracies which may occur from the use of third-party sources. If you have any queries regarding this article contact us
Fact-checking Policy
The Medical Education Network makes every effort to review and fact-check the articles used as source material in our summaries and original material. We have strict guidelines in relation to the publications we use as our source data, favouring peer-reviewed research wherever possible. Every effort is made to ensure that the information contained here is an accurate reflection of the original material. Should you find inaccuracies, out of date content or have any additional issues with our articles, please make use of the contact us form to notify us.
