In Brief | Four-Year Progression of Myopic Maculopathy in Children and Adolescents With High Myopia
Estimated read time: 1 minute, 13 seconds
Originally Published:25 January 2023
Sourced: JAMA Ophthalmology
Type of article: In Brief
MedED Catalogue Reference: MOIB008
Category: Ophthalmology
Cross Reference: Paediatrics
Keywords: high myopia, macular myopathy,
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Originally published in JAMA Ophthalmology
Macular myopia is one of the top causes of visual impairment globally. By the year 2020 it was estimated that 2.5 billion people were affected by the disease. 27%–33% of whom were expected to present with high myopia.1
While much attention has focused on the disease in adults, children or adolescents who present with the disease are at higher risk for progressively worsening macular myopathy.
This latest research by Jiang, & Wang et al. set out to investigate the progression of myopic maculopathy in this younger cohort (18 years or younger) and to determine the associated risk factors.
Their outcomes-based hospital study included 274 children between the ages of 7 and 17. Myopic maculopathy was accessed using the International Photographic Classification and Grading System and the individuals were followed-up over-up a 4-year period.
The researchers found that condition had progressed in 67 out of 548 eyes (12.2%) with enlargement of diffuse atrophy being the most prevalent progression (55.7%).
Additional lesion changes included tessellated fundus signs in 16 eyes (18.2%), diffuse atrophy in 12 eyes (13.6%), patchy atrophy in 2 eyes (2.3%), and lacquer cracks in 9 eyes (10.2%).
Risk factors for progression were determined as worse best-corrected visual acuity, longer axial length, faster axial length elongation and more severe myopic maculopathy diffuse atrophy and patchy atrophy.
The findings indicate the benefits of follow-up in this younger population, and for additional resources to identify those at higher risk for progression.
References
1.Ruiz-Medrano, J., Montero, J. A., Flores-Moreno, I., Arias, L., García-Layana, A., & Ruiz-Moreno, J. M. (2019). Myopic maculopathy: Current status and proposal for a new classification and grading system (ATN). Progress in retinal and eye research, 69, 80–115. https://doi.org/10.1016/j.preteyeres.2018.10.005
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