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Metformin Cessation and Dementia Incidence
The researchers aimed to explore whether terminating metformin in type 2 patients who did not have kidney disease was associated with dementia incidence.
Source: JAMA Network Open
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Association of Pathogenic DNA Variants Predisposing to Cardiomyopathy With Cardiovascular Disease Outcomes and All-Cause Mortality
In keeping with our theme this month of promoting early diagnosis, we’re focusing on a new trial published in JAMA Cardiology which reviewed the association of pathogenic DNA variants linked to the development of cardiomyopathy and the consequent outcomes of cardiovascular disease.
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Inflammation and cholesterol as predictors of cardiovascular events among patients receiving statin therapy: a collaborative analysis of three randomised trials
Time to read: 02:58 mins. Inflammation and hyperlipidaemia jointly contribute to atherothrombotic disease. However, in patients undergoing intensive statin therapy, the balance of influences of the two on future cardiovascular events may shift, which could have implications for the selection of additional cardiovascular treatments.
Source: The Lancet
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Associations of Change in Body Size With All-Cause and Cause-Specific Mortality Among Healthy Older Adults
Keywords associated with this article include: all risk mortality, cause-specific mortality, obesity, weight loss, geriatric health
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Clinical Manifestations of Early-Onset Dementia With Lewy Bodies Compared With Late-Onset Dementia With Lewy Bodies and Early-Onset Alzheimer Disease
Keywords associated with this article: gerontology, Lewy bodies, Dementia, early-onset dementia, late-onset dementia, Alzheimers
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Elective total hip arthroplasty in the elderly: Three studies reviewed
Keywords associated with this article: gerontoloy, total hip arthroplasty, osteoarthritis, public healthcare, burden of disease, hip fracture
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The Evaluation of Adiposity in Adults
This study reviews the link between adiposity in adults in the absence of cardiovascular risk factors. Source: JAMA Open Network. Publication Date: 1 February 2022
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Assessment of Plasma Phospholipid Very-Long-Chain Saturated Fatty Acid Levels and Healthy Aging.
A review of recent clinical research into the association of very long-chain saturated fatty acids (VLSFA), and a possible link to healthy ageing. Source: JAMA. Publication Date: 17 September 21
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