Published in 2019, *Superbugs* by Matt McCarthy is a gripping exploration of one of the greatest medical threats of our time: drug-resistant bacteria. The book is a compelling narrative about the race to combat these "superbugs" following McCarthy’s own groundbreaking clinical trial for a new antibiotic aimed at saving countless lives.
Through McCarthy’s personal journey in developing dalbavancin - an antimicrobial for the treatment of acute bacterial skin and skin structure infections caused by Gram +ve bacteria, - the book delves into the challenges of antimicrobial resistance, the medical history of antibiotics, and the ethics of drug development.
The story of McCarthy’s clinical trial serves as a hook to discuss broader issues, such as the high stakes of medical research, the slow pace of regulatory approval, and the financial barriers that prevent Big Pharma from investing in life-saving drugs.
He effectively brings to light the human impact of these issues by sharing the stories of patients like Remy, Donny, and his own father-in-law, each facing life-threatening infections.
Although published five years ago, Superbugs remains as relevant as ever. McCarthy's warnings about the dangers of antimicrobial resistance were somewhat prescient, but the urgency of these issues has only intensified post COVID. The book serves as both a sobering reminder and a call to action, urging us to focus our collective efforts on developing new treatments and combating antimicrobial resistance, which continues to threaten global health.
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Editorial Reviews
"An amazing, informative book that changes our perspective on medicine, microbes and our future."
--Siddhartha Mukherjee, MD, New York Times bestselling author of The Emperor of All Maladies